"a lord-master, a protector," c.1300, from O.Fr. patrun (12c.), from M.L. patronus "patron saint, bestower of a benefice, lord, master, model, pattern," from L. patronus "defender, protector, advocate," from pater (gen. patris) "father." Meaning "one who advances the cause" (of an artist, institution, etc.), usually by the person's wealth and power, is attested from late 14c.; "commonly a wretch who supports with insolence, and is paid with flattery" [Johnson]. Commercial sense of "regular customer" first recorded c.1600. Patron saint (1717) was originally simply patron (late 14c.).
1540s, "clean, free from dirt," from Anglo-Fr. neit, M.Fr. net "clear, pure," from L. nitidus "well-favored, elegant, trim," lit. "gleaming," from nitere "to shine," from PIE root *nei- "to shine" (cf. M.Ir. niam "gleam, splendor," niamda "shining;" O.Ir. noib "holy," niab "strength;" Welsh nwyfiant "gleam, splendor").
Meaning "inclined to be tidy" is from 1570s. Of liquor, "straight," c.1800, from meaning "unadulterated" (of wine), which is first attested 1570s. Informal sense of "very good" first recorded 1934 in American English; variant neato is teenager slang, first recorded 1968. Related: Neatly; neatness.